Phagolysosomal Simulant Fluid (PSF) or Artificial Phagolysosomal Body Fluid (BZ262)

This simulated fluid is only used in the field of scientific research and For in vitro use only.

Pack Size: 100 mL, 200 mL, 500 mL, 1000 mL

pH is 4.5 (can be customized on the request as per the customer’s project requirement)

Validity: 6 months

Transportation and storage: transportation at room temperature, storage at 2-8 ℃.

 

Phagolysosomal Simulant Fluid (PSF)  Features & Notes:

1. Phagolysosomal Simulant Fluid (PSF) is a sterile solution and can be used directly.
2. Phagolysosomal Simulant Fluid, stored at 4 degrees, transported at room temperature.
3. This Phagolysosomal Simulant Fluid is limited to the scientific research of professionals, and cannot be used for clinical diagnosis or treatment, and cannot be used for food or medicine, and cannot be stored in ordinary houses.
4. For your safety and health, please wear a lab coat and disposable gloves.

Lysosomes are acidic compartments filled with more than 60 different types of hydrolases. They mediate the degradation of extracellular particles from endocytosis and intracellular components from autophagy. The digested products are transported out of the lysosome via specific catabolite exporters or via vesicular membrane trafficking. Lysosomes also contain more than 50 membrane proteins and are equipped with the machinery to sense nutrient availability, which determines the distribution, number, size, and activity of lysosomes to control the specificity of cargo flux and timing (the initiation and termination) of degradation. Defects in degradation, export, or trafficking result in lysosomal dysfunction and lysosomal storage diseases (LSDs). Lysosomal channels and transporters mediate ion flux across perimeter membranes to regulate lysosomal ion homeostasis, membrane potential, catabolite export, membrane trafficking, and nutrient sensing. Dysregulation of lysosomal channels underlies the pathogenesis of many LSDs and possibly that of metabolic and common neurodegenerative diseases.

Volume	100ml, 200ml, 500ml, 1000ml